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DeCS
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Descriptor English:
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Mad2 Proteins
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Descriptor Spanish:
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Proteínas Mad2
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Descriptor Portuguese:
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Proteínas Mad2
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Synonyms English:
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Mad2 Mitotic Arrest Deficient-like 1 Proteins
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Tree Number:
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D12.776.167.313
D12.776.660.526
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Definition English:
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Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. |
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History Note English:
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2014
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Allowable Qualifiers English:
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Record Number:
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55327
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Unique Identifier:
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D064246
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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